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Open Access
Peer-reviewed
Research Article
Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers
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Gareth A. D. Hardy,
Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Scott Sieg,
Affiliations Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Benigno Rodriguez,
Affiliations Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Donald Anthony,
Affiliations Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Cleveland Veterans’ Administration Medical Center, Cleveland, Ohio, United States of America
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Robert Asaad,
Affiliations Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Wei Jiang,
Affiliations Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Joseph Mudd,
Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Timothy Schacker,
Affiliation Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America
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Nicholas T. Funderburg,
Affiliation Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Heather A. Pilch-Cooper,
Affiliation Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Robert Debernardo,
Affiliation Department of Obstetrics & Gynecology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Ronald L. Rabin,
Affiliation Laboratory of Immunobiochemistry, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland, United States of America
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Michael M. Lederman,
Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Clifford V. Harding
* E-mail: cvh3@cwru.edu
Affiliations Department of Pathology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Department of Medicine, Division of Infectious Diseases, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America, Center for AIDS Research, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio, United States of America
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Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers
- Gareth A. D. Hardy,
- Scott Sieg,
- Benigno Rodriguez,
- Donald Anthony,
- Robert Asaad,
- Wei Jiang,
- Joseph Mudd,
- Timothy Schacker,
- Nicholas T. Funderburg,
- Heather A. Pilch-Cooper
- Published: February 20, 2013
- https://doi.org/10.1371/journal.pone.0056527