Mouse Zygotes Respond to Severe Sperm DNA Damage by Delaying Paternal DNA Replication and Embryonic Development

Open Access

Peer-reviewed

Research Article

Joanna E. Gawecka,

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Joel Marh,

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Michael Ortega,

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Yasuhiro Yamauchi,

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Monika A. Ward,

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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W. Steven Ward

* E-mail: wward@hawaii.edu

Affiliation Institute for Biogenesis Research, Department of Anatomy, Biochemistry and Physiology, University of Hawaii at Manoa, John A. Burns School of Medicine, Honolulu, Hawaii, United States of America
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Zygotes
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Sperm
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DNA damage
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Embryos
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DNA replication
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Oocytes
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Chromatin
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Apoptosis
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