Clearance and Toxicity of Recombinant Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (r-metHu GDNF) Following Acute Convection-Enhanced Delivery into the Striatum

• Hannah Taylor,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

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• Neil Barua,

  Affiliations School of Clinical Sciences, University of Bristol, Bristol, United Kingdom, Department of Neurosurgery, Frenchay Hospital, Bristol, United Kingdom

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• Alison Bienemann,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

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• Marcella Wyatt,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

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• Emma Castrique,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

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• Rebecca Foster,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

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• Matthias Luz,

  Affiliation MedGenesis Therapeutix Inc., Victoria, British Columbia, Canada

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• Christian Fibiger,

  Affiliation MedGenesis Therapeutix Inc., Victoria, British Columbia, Canada

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• Erich Mohr,

  Affiliation MedGenesis Therapeutix Inc., Victoria, British Columbia, Canada

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• Steven Gill

  * E-mail: steven.gill@nbt.nhs.uk.

  Affiliations School of Clinical Sciences, University of Bristol, Bristol, United Kingdom, Department of Neurosurgery, Frenchay Hospital, Bristol, United Kingdom

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