Curcumin Down-Regulates DNA Methyltransferase 1 and Plays an Anti-Leukemic Role in Acute Myeloid Leukemia

• Jianhua Yu ,

  * E-mail: Jianhua.yu@osumc.edu (JY); liu.550@osu.edu (ZL)

  Affiliations Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Yong Peng,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Lai-Chu Wu,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America

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• Zhiliang Xie,

  Affiliation Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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• Youcai Deng,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, College of Pharmacy, Third Military Medical University, Chongqing, China

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• Tiffany Hughes,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Shun He,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• XiaoKui Mo,

  Affiliation Center for Biostatistics, The Ohio State University, Columbus, Ohio, United States of America

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• Ming Chiu,

  Affiliation Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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• Qi-En Wang,

  Affiliation Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Xiaoming He,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, United States of America

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• Shujun Liu,

  Affiliation The Hormel Institute, University of Minnesota, Austin, Minnesota, United States of America

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• Michael R. Grever,

  Affiliations Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America

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• Kenneth K. Chan,

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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• Zhongfa Liu

  * E-mail: Jianhua.yu@osumc.edu (JY); liu.550@osu.edu (ZL)

  Affiliations Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America, Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio, United States of America

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