BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival of Human Prostate Cancer Cells

Christopher G. Low; Iris S. U. Luk; Dong Lin; Ladan Fazli; Kuo Yang; Yong Xu; Martin Gleave; Peter W. Gout; Yuzhuo Wang

doi:10.1371/journal.pone.0055837

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Open Access

Peer-reviewed

Research Article

BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival of Human Prostate Cancer Cells

Christopher G. Low ,

Contributed equally to this work with: Christopher G. Low, Iris S. U. Luk

Affiliations The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada, Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada
⨯
Iris S. U. Luk ,

Contributed equally to this work with: Christopher G. Low, Iris S. U. Luk

Affiliations The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada, Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada
⨯
Dong Lin,

Affiliations The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada, Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada
⨯
Ladan Fazli,

Affiliation The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada
⨯
Kuo Yang,

Affiliations The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada, Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China
⨯
Yong Xu,

Affiliation Department of Urology, The Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China
⨯
Martin Gleave,

Affiliation The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada
⨯
Peter W. Gout,

Affiliation Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada
⨯
Yuzhuo Wang

* E-mail: ywang@bccrc.ca

Affiliations The Vancouver Prostate Centre, Vancouver General Hospital and Department of Urologic Sciences, the University of British Columbia, Vancouver, British Columbia, Canada, Department of Experimental Therapeutics, BC Cancer Agency, Vancouver, British Columbia, Canada
⨯

BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival of Human Prostate Cancer Cells

Christopher G. Low,
Iris S. U. Luk,
Dong Lin,
Ladan Fazli,
Kuo Yang,
Yong Xu,
Martin Gleave,
Peter W. Gout,
Yuzhuo Wang

Published: February 8, 2013
https://doi.org/10.1371/journal.pone.0055837

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Apoptosis
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Small interfering RNA
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Autophagic cell death
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Protein expression
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