Integrity of p53 Associated Pathways Determines Induction of Apoptosis of Tumor Cells Resistant to Aurora-A Kinase Inhibitors

Open Access

Peer-reviewed

Research Article

Yoshimi Shionome,

Affiliation Department of Medicine, National University of Health Sciences, Pritzker School of Medicine, The University of Chicago, Evanston, Illinois, United States of America
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Li Yan,

Affiliation Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, New York, United States of America
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Song Liu,

Affiliation Department of Biostatistics and Bioinformatics, Roswell Park Cancer Institute, Buffalo, New York, United States of America
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Toshiaki Saeki,

Affiliation Department of Breast Oncology, Saitama International Medical Center, Hidaka, Saitama, Japan
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Toru Ouchi

* E-mail: Toru.Ouchi@RoswellPark.org

Affiliations Department of Medicine, National University of Health Sciences, Pritzker School of Medicine, The University of Chicago, Evanston, Illinois, United States of America, Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, New York, United States of America
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Malignant tumors
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Apoptosis
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Cancer treatment
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Cancers and neoplasms
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Carcinogenesis
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Cloning
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Breast cancer
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Mouse models
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