Identification and Characterization of Calcium Sparks in Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

Open Access

Peer-reviewed

Research Article

Guang Qin Zhang ,

Contributed equally to this work with: Guang Qin Zhang, Heming Wei

Affiliations Research and Development Unit, National Heart Centre Singapore, Singapore, Republic of Singapore, Department of Clinical Pharmacy, China Pharmaceutical University, Nanjing, China
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Heming Wei ,

Contributed equally to this work with: Guang Qin Zhang, Heming Wei

Affiliations Research and Development Unit, National Heart Centre Singapore, Singapore, Republic of Singapore, Cardiovascular and Metabolic Disorders Program, DUKE-NUS Graduate Medical School Singapore, Singapore, Republic of Singapore
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Jun Lu,

Affiliation Research and Development Unit, National Heart Centre Singapore, Singapore, Republic of Singapore
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Philip Wong,

Affiliations Research and Development Unit, National Heart Centre Singapore, Singapore, Republic of Singapore, Cardiovascular and Metabolic Disorders Program, DUKE-NUS Graduate Medical School Singapore, Singapore, Republic of Singapore
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Winston Shim

* E-mail: winston.shim.s.n@nhcs.com.sg

Affiliations Research and Development Unit, National Heart Centre Singapore, Singapore, Republic of Singapore, Cardiovascular and Metabolic Disorders Program, DUKE-NUS Graduate Medical School Singapore, Singapore, Republic of Singapore
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Cardiomyocytes
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Muscle cells
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Cell differentiation
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Fluorescence imaging
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Action potentials
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DAPI staining
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Induced pluripotent stem cells
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Pluripotency
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