Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia

Quan-Xiang Wei; Rainer Claus; Thomas Hielscher; Daniel Mertens; Aparna Raval; Christopher C. Oakes; Stephan M. Tanner; Albert de la Chapelle; John C. Byrd; Stephan Stilgenbauer; Christoph Plass

doi:10.1371/journal.pone.0055261

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Open Access

Peer-reviewed

Research Article

Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia

Quan-Xiang Wei ,

Contributed equally to this work with: Quan-Xiang Wei, Rainer Claus

Affiliation Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany
⨯
Rainer Claus ,

Contributed equally to this work with: Quan-Xiang Wei, Rainer Claus

* E-mail: r.claus@dkfz.de

Affiliations Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany, Department of Hematology/Oncology, University of Freiburg Medical Center, Freiburg, Germany
⨯
Thomas Hielscher,

Affiliation Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany
⨯
Daniel Mertens,

Affiliations Cooperation Unit “Mechanisms of Leukemogenesis”, German Cancer Research Center (DKFZ), Heidelberg, Germany, Department of Internal Medicine III, University of Ulm, Ulm, Germany
⨯
Aparna Raval,

Affiliation Cancer Center, Stanford University, Stanford, California, United States of America
⨯
Christopher C. Oakes,

Affiliation Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany
⨯
Stephan M. Tanner,

Affiliation Department of Molecular Virology, Immunology, and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
Albert de la Chapelle,

Affiliation Department of Molecular Virology, Immunology, and Medical Genetics, Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
John C. Byrd,

Affiliation Department of Internal Medicine, Division of Hematology, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
⨯
Stephan Stilgenbauer,

Affiliation Department of Internal Medicine III, University of Ulm, Ulm, Germany
⨯
Christoph Plass

Affiliation Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany
⨯

Germline Allele-Specific Expression of DAPK1 in Chronic Lymphocytic Leukemia

Quan-Xiang Wei,
Rainer Claus,
Thomas Hielscher,
Daniel Mertens,
Aparna Raval,
Christopher C. Oakes,
Stephan M. Tanner,
Albert de la Chapelle,
John C. Byrd,
Stephan Stilgenbauer

Published: January 28, 2013
https://doi.org/10.1371/journal.pone.0055261

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DNA methylation
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Single nucleotide polymorphisms
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Heterozygosity
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