Androgen Signaling Promotes Translation of TMEFF2 in Prostate Cancer Cells via Phosphorylation of the α Subunit of the Translation Initiation Factor 2

Ryan F. Overcash; Vesna A. Chappell; Thomas Green; Christopher B. Geyer; Adam S. Asch; Maria J. Ruiz-Echevarría

doi:10.1371/journal.pone.0055257

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Peer-reviewed

Research Article

Androgen Signaling Promotes Translation of TMEFF2 in Prostate Cancer Cells via Phosphorylation of the α Subunit of the Translation Initiation Factor 2

Ryan F. Overcash,

Affiliation Department of Biochemistry and Molecular Biology, Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America
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Vesna A. Chappell,

Affiliation Department of Anatomy and Cell Biology, Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America
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Thomas Green,

Affiliation Department of Internal Medicine, Division of Hematology/Oncology. Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America
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Christopher B. Geyer,

Affiliation Department of Anatomy and Cell Biology, Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America
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Adam S. Asch,

Affiliations Department of Internal Medicine, Division of Hematology/Oncology. Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Maria J. Ruiz-Echevarría

* E-mail: ruizechevarriam@ecu.edu

Affiliations Department of Anatomy and Cell Biology, Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America, Department of Internal Medicine, Division of Hematology/Oncology. Brody School of Medicine at East Carolina University, Greenville, North Carolina, United States of America, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Androgen Signaling Promotes Translation of TMEFF2 in Prostate Cancer Cells via Phosphorylation of the α Subunit of the Translation Initiation Factor 2

Ryan F. Overcash,
Vesna A. Chappell,
Thomas Green,
Christopher B. Geyer,
Adam S. Asch,
Maria J. Ruiz-Echevarría

Published: February 6, 2013
https://doi.org/10.1371/journal.pone.0055257

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Prostate cancer
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Androgens
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Protein translation
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Messenger RNA
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Phosphorylation
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Luciferase
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Translation initiation
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Transcriptional control
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