Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

Francesca Colleoni; Nisha Padmanabhan; Hong-wa Yung; Erica D. Watson; Irene Cetin; Martha C. Tissot van Patot; Graham J. Burton; Andrew J. Murray

doi:10.1371/journal.pone.0055194

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Open Access

Peer-reviewed

Research Article

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

Francesca Colleoni ,

* E-mail: fc316@cam.ac.uk

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Nisha Padmanabhan ,

Contributed equally to this work with: Nisha Padmanabhan, Hong-wa Yung

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Hong-wa Yung ,

Contributed equally to this work with: Nisha Padmanabhan, Hong-wa Yung

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Erica D. Watson,

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Irene Cetin,

Affiliation Unit of Obstetrics and Gynecology, Department of Clinical Sciences “Luigi Sacco”, University of Milan, Milan, Italy
⨯
Martha C. Tissot van Patot,

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Graham J. Burton,

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯
Andrew J. Murray

Affiliation Department of Physiology, Development & Neuroscience, and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom
⨯

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

Francesca Colleoni,
Nisha Padmanabhan,
Hong-wa Yung,
Erica D. Watson,
Irene Cetin,
Martha C. Tissot van Patot,
Graham J. Burton,
Andrew J. Murray

Published: January 30, 2013
https://doi.org/10.1371/journal.pone.0055194

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29 Nov 2013
11:49 GMT
Most Recent

Correction to Figure Legends Posted by Andrew_Murray on 29 Nov 2013 at 11:49 GMT

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Fibroblasts
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Hypoxia
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