TLR-9 Contributes to the Antiviral Innate Immune Sensing of Rodent Parvoviruses MVMp and H-1PV by Normal Human Immune Cells

Zahari Raykov; Svitlana P. Grekova; Rita Hörlein; Barbara Leuchs; Thomas Giese; Nathalia A. Giese; Jean Rommelaere; Rainer Zawatzky; Laurent Daeffler

doi:10.1371/journal.pone.0055086

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Peer-reviewed

Research Article

TLR-9 Contributes to the Antiviral Innate Immune Sensing of Rodent Parvoviruses MVMp and H-1PV by Normal Human Immune Cells

Zahari Raykov,

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯
Svitlana P. Grekova,

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯
Rita Hörlein,

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯
Barbara Leuchs,

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯
Thomas Giese,

Affiliation Institute of Immunology, University Hospital Heidelberg, Heidelberg, Germany
⨯
Nathalia A. Giese,

Affiliation Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany
⨯
Jean Rommelaere,

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯
Rainer Zawatzky,

Affiliation Infection and Cancer Program, Division F030 Department Viral Transformation Mechanisms, German Cancer Research Center, Heidelberg, Germany
⨯
Laurent Daeffler

* E-mail: l.daeffler@dkfz.de

Affiliation Infection and Cancer Program, Division F010 and Institut National de la Santé et de la Recherche Médicale INSERM U701, German Cancer Research Center, Heidelberg, Germany
⨯

TLR-9 Contributes to the Antiviral Innate Immune Sensing of Rodent Parvoviruses MVMp and H-1PV by Normal Human Immune Cells

Zahari Raykov,
Svitlana P. Grekova,
Rita Hörlein,
Barbara Leuchs,
Thomas Giese,
Nathalia A. Giese,
Jean Rommelaere,
Rainer Zawatzky,
Laurent Daeffler

Published: January 29, 2013
https://doi.org/10.1371/journal.pone.0055086

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Toll-like receptors
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DNA replication
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Rodents
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Antiviral immune response
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