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Open Access
Peer-reviewed
Research Article
Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers
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Maria B. Raeder ,
* E-mail: Maria.Rader@uib.no
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway, Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
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Even Birkeland,
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Jone Trovik,
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Camilla Krakstad,
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Shyemaa Shehata,
Affiliation Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
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Steven Schumacher,
Affiliations Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, The Broad Institute, Cambridge, Massachusetts, United States of America
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Travis I. Zack,
Affiliations Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, The Broad Institute, Cambridge, Massachusetts, United States of America, Department of Biophysics, Harvard University, Boston, Massachusetts, United States of America
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Antje Krohn,
Affiliation Department of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg-Eppendorf, Germany
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Henrica MJ. Werner,
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Susan E. Moody,
Affiliations Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, The Broad Institute, Cambridge, Massachusetts, United States of America
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Elisabeth Wik,
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Ingunn M. Stefansson,
Affiliations The Gade Institute, University of Bergen, Bergen, Norway, Department of Pathology, Haukeland University Hospital, Bergen, Norway
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Frederik Holst,
Affiliation Department of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg-Eppendorf, Germany
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Anne M. Oyan,
Affiliations The Gade Institute, University of Bergen, Bergen, Norway, Department of Microbiology and Immunology, Haukeland University Hospital, Bergen, Norway
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Pablo Tamayo,
Affiliation The Broad Institute, Cambridge, Massachusetts, United States of America
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Jill P. Mesirov,
Affiliation The Broad Institute, Cambridge, Massachusetts, United States of America
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Karl H. Kalland,
Affiliations The Gade Institute, University of Bergen, Bergen, Norway, Department of Microbiology and Immunology, Haukeland University Hospital, Bergen, Norway
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Lars A. Akslen,
Affiliations The Gade Institute, University of Bergen, Bergen, Norway, Department of Pathology, Haukeland University Hospital, Bergen, Norway
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Ronald Simon,
Affiliation Department of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg-Eppendorf, Germany
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Rameen Beroukhim ,
Contributed equally to this work with: Rameen Beroukhim, Helga B. Salvesen
Affiliations Department of Cancer Biology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, The Broad Institute, Cambridge, Massachusetts, United States of America, Departments of Medicine, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts, United States of America
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Helga B. Salvesen
Contributed equally to this work with: Rameen Beroukhim, Helga B. Salvesen
Affiliations Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway, Department of Clinical Medicine, University of Bergen, Bergen, Norway
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Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers
- Maria B. Raeder,
- Even Birkeland,
- Jone Trovik,
- Camilla Krakstad,
- Shyemaa Shehata,
- Steven Schumacher,
- Travis I. Zack,
- Antje Krohn,
- Henrica MJ. Werner,
- Susan E. Moody
- Published: February 5, 2013
- https://doi.org/10.1371/journal.pone.0054873