High Doses of Romiplostim Induce Proliferation and Reduce Proplatelet Formation by Human Megakaryocytes

Open Access

Peer-reviewed

Research Article

Manuela Currao,

Affiliation Dept. of Molecular Medicine, Biotechnology Laboratories, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy
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Carlo L. Balduini,

Affiliation Dept. of Internal Medicine, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy
⨯
Alessandra Balduini

* E-mail: alessandra.balduini@unipv.it

Affiliations Dept. of Molecular Medicine, Biotechnology Laboratories, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy, Dept. of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America
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Ploidy
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Cell differentiation
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Megakaryocytes
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Platelets
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Blood
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MAPK signaling cascades
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Umbilical cord
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Thrombocytopenia
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