Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

Chenxi Liu; Liqin Wang; Wenrong Li; Xuemei Zhang; Yongzhi Tian; Ning Zhang; Sangang He; Tong Chen; Juncheng Huang; Mingjun Liu

doi:10.1371/journal.pone.0054614

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Open Access

Peer-reviewed

Research Article

Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

Chenxi Liu,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, College of Life Science and Technology, Xinjiang University, Urumqi, Xinjiang, China
⨯
Liqin Wang,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Wenrong Li,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Xuemei Zhang,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Yongzhi Tian,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Ning Zhang,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Sangang He,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Tong Chen,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Juncheng Huang,

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯
Mingjun Liu

* E-mail: mingjun_1@sina.com

Affiliations Xinjiang Laboratory of Animal Biotechnology, Urumqi, Xinjiang, China, Key Laboratory of Genetics, Breeding and Reproduction of Grass Feeding Livestock, Ministry of Agriculture, Urumqi, Xinjiang, China, Animal Biotechnology Research Center, Xinjiang Academy of Animal Science, Urumqi, Xinjiang, China
⨯

Highly Efficient Generation of Transgenic Sheep by Lentivirus Accompanying the Alteration of Methylation Status

Chenxi Liu,
Liqin Wang,
Wenrong Li,
Xuemei Zhang,
Yongzhi Tian,
Ning Zhang,
Sangang He,
Tong Chen,
Juncheng Huang,
Mingjun Liu

Published: January 29, 2013
https://doi.org/10.1371/journal.pone.0054614

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