Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis

Christoph Roderburg; Mark Luedde; David Vargas Cardenas; Mihael Vucur; David Scholten; Norbert Frey; Alexander Koch; Christian Trautwein; Frank Tacke; Tom Luedde

doi:10.1371/journal.pone.0054612

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Open Access

Peer-reviewed

Research Article

Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis

Christoph Roderburg ,

Contributed equally to this work with: Christoph Roderburg, Mark Luedde

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Mark Luedde ,

Contributed equally to this work with: Christoph Roderburg, Mark Luedde

Affiliation Department of Cardiology and Angiology, University of Kiel, Kiel, Germany
⨯
David Vargas Cardenas,

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Mihael Vucur,

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
David Scholten,

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Norbert Frey,

Affiliation Department of Cardiology and Angiology, University of Kiel, Kiel, Germany
⨯
Alexander Koch,

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Christian Trautwein,

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Frank Tacke ,

¶These authors also contributed equally to this work.

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯
Tom Luedde

* E-mail: tluedde@ukaachen.de

¶These authors also contributed equally to this work.

Affiliation Department of Medicine III, University Hospital Rheinisch-Westfaelische Technische Hochschule (RWTH) Aachen, Aachen, Germany
⨯

Circulating MicroRNA-150 Serum Levels Predict Survival in Patients with Critical Illness and Sepsis

Christoph Roderburg,
Mark Luedde,
David Vargas Cardenas,
Mihael Vucur,
David Scholten,
Norbert Frey,
Alexander Koch,
Christian Trautwein,
Frank Tacke,
Tom Luedde

Published: January 23, 2013
https://doi.org/10.1371/journal.pone.0054612

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Sepsis
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Intensive care units
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MicroRNAs
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Death rates
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Inflammation
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Gene expression
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