High Glucose Induced Alteration of SIRTs in Endothelial Cells Causes Rapid Aging in a p300 and FOXO Regulated Pathway

Open Access

Peer-reviewed

Research Article

Rokhsana Mortuza,

Affiliation Department of Pathology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
⨯
Shali Chen,

Affiliation Department of Pathology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
⨯
Biao Feng,

Affiliation Department of Pathology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
⨯
Subhrojit Sen,

Affiliation Department of Pathology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
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Subrata Chakrabarti

* E-mail: subrata.chakrabarti@schulich.uwo.ca

Affiliation Department of Pathology, Schulich School of Medicine & Dentistry, University of Western Ontario, London, Ontario, Canada
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Glucose
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Diabetes mellitus
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Gene expression
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Small interfering RNA
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Oxidative stress
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Kidneys
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Cell staining
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Endothelial cells
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