The Insulin-Like Growth Factor 1 Receptor Is Essential for Axonal Regeneration in Adult Central Nervous System Neurons

Sebastián Dupraz; Diego Grassi; Diana Karnas; Alvaro F. Nieto Guil; David Hicks; Santiago Quiroga

doi:10.1371/journal.pone.0054462

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Peer-reviewed

Research Article

The Insulin-Like Growth Factor 1 Receptor Is Essential for Axonal Regeneration in Adult Central Nervous System Neurons

Sebastián Dupraz ,

Contributed equally to this work with: Sebastián Dupraz, Diego Grassi

Affiliation Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba y Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina
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Diego Grassi ,

Contributed equally to this work with: Sebastián Dupraz, Diego Grassi

Affiliation Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba y Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina
⨯
Diana Karnas,

Affiliation Rhythms, Life and Death in the Retina, Centre National de la Recherche Scientifique (CNRS) UPR-3212 Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France
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Alvaro F. Nieto Guil,

Affiliation Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba y Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina
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David Hicks,

Affiliation Rhythms, Life and Death in the Retina, Centre National de la Recherche Scientifique (CNRS) UPR-3212 Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, Strasbourg, France
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Santiago Quiroga

* E-mail: squiroga@fcq.unc.edu.ar

Affiliation Departamento de Química Biológica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba y Centro de Investigaciones en Química Biológica de Córdoba (CIQUIBIC), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina
⨯

The Insulin-Like Growth Factor 1 Receptor Is Essential for Axonal Regeneration in Adult Central Nervous System Neurons

Sebastián Dupraz,
Diego Grassi,
Diana Karnas,
Alvaro F. Nieto Guil,
David Hicks,
Santiago Quiroga

Published: January 18, 2013
https://doi.org/10.1371/journal.pone.0054462

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Retinal ganglion cells
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Axons
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Nerve regeneration
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Central nervous system
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Neurons
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Transfection
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Retina
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Neuronal differentiation
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