HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

Kristin Eissmann; Sebastian Mueller; Heinrich Sticht; Susan Jung; Peng Zou; Shibo Jiang; Andrea Gross; Jutta Eichler; Bernhard Fleckenstein; Heide Reil

doi:10.1371/journal.pone.0054452

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Peer-reviewed

Research Article

HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

Kristin Eissmann,

Affiliation Institute of Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Sebastian Mueller,

Affiliation Institute of Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Heinrich Sticht,

Affiliation Bioinformatics, Institute of Biochemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Susan Jung,

Affiliation Institute of Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Peng Zou,

Affiliation Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America
⨯
Shibo Jiang,

Affiliations Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America, Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College, Institute of Medical Microbiology, Fudan University, Shanghai, China
⨯
Andrea Gross,

Affiliation Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Jutta Eichler,

Affiliation Medicinal Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Bernhard Fleckenstein,

Affiliation Institute of Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Heide Reil

* E-mail: heide.reil@viro.med.uni-erlangen.de

Affiliation Institute of Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯

HIV-1 Fusion Is Blocked through Binding of GB Virus C E2D Peptides to the HIV-1 gp41 Disulfide Loop

Kristin Eissmann,
Sebastian Mueller,
Heinrich Sticht,
Susan Jung,
Peng Zou,
Shibo Jiang,
Andrea Gross,
Jutta Eichler,
Bernhard Fleckenstein,
Heide Reil

Published: January 22, 2013
https://doi.org/10.1371/journal.pone.0054452

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