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Open Access

Peer-reviewed

Research Article

BIRB796, the Inhibitor of p38 Mitogen-Activated Protein Kinase, Enhances the Efficacy of Chemotherapeutic Agents in ABCB1 Overexpression Cells

Dan He,

Affiliation Department of Thoracic Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumuqi, China
⨯
Xiao-qin Zhao,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Xing-gui Chen,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Yi Fang,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Satyakam Singh,

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, United States of America
⨯
Tanaji T. Talele,

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, United States of America
⨯
Hui-juan Qiu,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Yong-ju Liang,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Xiao-kun Wang,

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯
Guo-qing Zhang ,

* E-mail: Fulw@mail.sysu.edu.cn (LF); zgqprofessor@sina.com (GZ)

Affiliation Department of Thoracic Surgery, Affiliated Tumor Hospital, Xinjiang Medical University, Urumuqi, China
⨯
Zhe-sheng Chen,

Affiliation Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, United States of America
⨯
Li-wu Fu

* E-mail: Fulw@mail.sysu.edu.cn (LF); zgqprofessor@sina.com (GZ)

Affiliation State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat-Sen University, Guangzhou, China
⨯

BIRB796, the Inhibitor of p38 Mitogen-Activated Protein Kinase, Enhances the Efficacy of Chemotherapeutic Agents in ABCB1 Overexpression Cells

Dan He,
Xiao-qin Zhao,
Xing-gui Chen,
Yi Fang,
Satyakam Singh,
Tanaji T. Talele,
Hui-juan Qiu,
Yong-ju Liang,
Xiao-kun Wang,
Guo-qing Zhang

x

Published: January 18, 2013
https://doi.org/10.1371/journal.pone.0054181

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Adenosine triphosphatase
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Small interfering RNA
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Cancer treatment
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Cancers and neoplasms
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Chemotherapeutic agents
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MTT assay
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Renal cancer
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Drug interactions
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