Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

Joseph M. D. Rastrick; Christopher S. Stevenson; Suffwan Eltom; Megan Grace; Meirion Davies; Iain Kilty; Steven M. Evans; Manolis Pasparakis; Matthew C. Catley; Toby Lawrence; Ian M. Adcock; Maria G. Belvisi; Mark A. Birrell

doi:10.1371/journal.pone.0054128

Loading metrics

Open Access

Peer-reviewed

Research Article

Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

Joseph M. D. Rastrick,

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Christopher S. Stevenson,

Affiliations Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom, Roche, Nutley, New Jersey, United States of America
⨯
Suffwan Eltom,

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Megan Grace,

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Meirion Davies,

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Iain Kilty,

Affiliation Pfizer, Pfizer Inc, Cambridge, Massachusetts, United States of America
⨯
Steven M. Evans,

Affiliation Pfizer, Pfizer Inc, Cambridge, Massachusetts, United States of America
⨯
Manolis Pasparakis,

Affiliation University of Cologne, Cologne, Germany
⨯
Matthew C. Catley,

Affiliation AstraZeneca, Molndal, Sweden, United Kingdom
⨯
Toby Lawrence,

Affiliation Centre d'Immunologie Marseille-Luminy, Marseille, France
⨯
Ian M. Adcock,

Affiliation Airway Disease, Imperial College London, United Kingdom
⨯
Maria G. Belvisi ,

* E-mail: m.belvisi@imperial.ac.uk

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯
Mark A. Birrell

Affiliation Respiratory Pharmacology, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom
⨯

Cigarette Smoke Induced Airway Inflammation Is Independent of NF-κB Signalling

Joseph M. D. Rastrick,
Christopher S. Stevenson,
Suffwan Eltom,
Megan Grace,
Meirion Davies,
Iain Kilty,
Steven M. Evans,
Manolis Pasparakis,
Matthew C. Catley,
Toby Lawrence

Published: January 22, 2013
https://doi.org/10.1371/journal.pone.0054128

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Chronic obstructive pulmonary disease
Is the Subject Area "Chronic obstructive pulmonary disease" applicable to this article?

Thanks for your feedback.
Epithelial cells
Is the Subject Area "Epithelial cells" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Smoking habits
Is the Subject Area "Smoking habits" applicable to this article?

Thanks for your feedback.
Lung development
Is the Subject Area "Lung development" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.