Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting

Xia Chuai; Hong Chen; Wen Wang; Yao Deng; Bo Wen; Li Ruan; Wenjie Tan

doi:10.1371/journal.pone.0054126

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Open Access

Peer-reviewed

Research Article

Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting

Xia Chuai ,

Contributed equally to this work with: Xia Chuai, Hong Chen

Affiliations National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China, Department of Microbiology, Hebei Medical University, Shijiazhuang, Heibei Province, People’s Republic of China
⨯
Hong Chen ,

Contributed equally to this work with: Xia Chuai, Hong Chen

Affiliation National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Wen Wang,

Affiliation National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Yao Deng,

Affiliation National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Bo Wen,

Affiliations National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China, College of Life Science, Jilin University, Changchun,Jinlin Province, People’s Republic of China
⨯
Li Ruan,

Affiliation National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯
Wenjie Tan

* E-mail: tanwj28@yahoo.cn

Affiliation National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China
⨯

Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting

Xia Chuai,
Hong Chen,
Wen Wang,
Yao Deng,
Bo Wen,
Li Ruan,
Wenjie Tan

Published: January 15, 2013
https://doi.org/10.1371/journal.pone.0054126

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