Genome-Wide Analysis of miRNA Signature Differentially Expressed in Doxorubicin-Resistant and Parental Human Hepatocellular Carcinoma Cell Lines

Jufeng Zhang; Ying Wang; Pingping Zhen; Xia Luo; Chao Zhang; Lin Zhou; Yanxin Lu; Yang Yang; Wei Zhang; Jun Wan

doi:10.1371/journal.pone.0054111

Loading metrics

Open Access

Peer-reviewed

Research Article

Genome-Wide Analysis of miRNA Signature Differentially Expressed in Doxorubicin-Resistant and Parental Human Hepatocellular Carcinoma Cell Lines

Jufeng Zhang ,

Contributed equally to this work with: Jufeng Zhang, Ying Wang

* E-mail: jfzhang111@163.com (JZ); zhangweispace@gmail.com (WZ); wanj@ust.hk (JW)

Affiliations Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China, School of Life Science, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Ying Wang ,

Contributed equally to this work with: Jufeng Zhang, Ying Wang

Affiliation Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China
⨯
Pingping Zhen,

Affiliation Key Lab of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Xia Luo,

Affiliation College of Engineering, South China Agricultural University, Guangzhou, China
⨯
Chao Zhang,

Affiliation Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China
⨯
Lin Zhou,

Affiliation School of Life Science, Guangdong Pharmaceutical University, Guangzhou, China
⨯
Yanxin Lu,

Affiliation Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China
⨯
Yang Yang,

Affiliation Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China
⨯
Wei Zhang ,

* E-mail: jfzhang111@163.com (JZ); zhangweispace@gmail.com (WZ); wanj@ust.hk (JW)

Affiliation Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China
⨯
Jun Wan

* E-mail: jfzhang111@163.com (JZ); zhangweispace@gmail.com (WZ); wanj@ust.hk (JW)

Affiliations Biomedical Research Institute, Shenzhen-PKU-HKUST Medical Center, Shenzhen, China, Division of Life Science, Hong Kong University of Science and Technology, Hong Kong, China
⨯

Genome-Wide Analysis of miRNA Signature Differentially Expressed in Doxorubicin-Resistant and Parental Human Hepatocellular Carcinoma Cell Lines

Jufeng Zhang,
Ying Wang,
Pingping Zhen,
Xia Luo,
Chao Zhang,
Lin Zhou,
Yanxin Lu,
Yang Yang,
Wei Zhang,
Jun Wan

Published: January 24, 2013
https://doi.org/10.1371/journal.pone.0054111

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Hepatocellular carcinoma
Is the Subject Area "Hepatocellular carcinoma" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Small nucleolar RNA
Is the Subject Area "Small nucleolar RNA" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
MAPK signaling cascades
Is the Subject Area "MAPK signaling cascades" applicable to this article?

Thanks for your feedback.