Low-Power Laser Irradiation Suppresses Inflammatory Response of Human Adipose-Derived Stem Cells by Modulating Intracellular Cyclic AMP Level and NF-κB Activity

Jyun-Yi Wu; Chia-Hsin Chen; Chau-Zen Wang; Mei-Ling Ho; Ming-Long Yeh; Yan-Hsiung Wang

doi:10.1371/journal.pone.0054067

Loading metrics

Open Access

Peer-reviewed

Research Article

Low-Power Laser Irradiation Suppresses Inflammatory Response of Human Adipose-Derived Stem Cells by Modulating Intracellular Cyclic AMP Level and NF-κB Activity

Jyun-Yi Wu ,

Contributed equally to this work with: Jyun-Yi Wu, Chia-Hsin Chen

Affiliation Institute of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan, Republic of China
⨯
Chia-Hsin Chen ,

Contributed equally to this work with: Jyun-Yi Wu, Chia-Hsin Chen

Affiliations Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, Republic of China, Department of Physical Medicine and Rehabilitation, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physical Medicine and Rehabilitation, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan, Republic of China
⨯
Chau-Zen Wang,

Affiliations Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Mei-Ling Ho,

Affiliations Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Department of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯
Ming-Long Yeh ,

* E-mail: mlyeh@mail.ncku.edu.tw (MLY); yhwang@kmu.edu.tw (YHW)

Affiliation Institute of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan, Republic of China
⨯
Yan-Hsiung Wang

* E-mail: mlyeh@mail.ncku.edu.tw (MLY); yhwang@kmu.edu.tw (YHW)

Affiliations Orthopaedic Research Center, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China, School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China
⨯

Low-Power Laser Irradiation Suppresses Inflammatory Response of Human Adipose-Derived Stem Cells by Modulating Intracellular Cyclic AMP Level and NF-κB Activity

Jyun-Yi Wu,
Chia-Hsin Chen,
Chau-Zen Wang,
Mei-Ling Ho,
Ming-Long Yeh,
Yan-Hsiung Wang

Published: January 16, 2013
https://doi.org/10.1371/journal.pone.0054067

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Cytokine therapy
Is the Subject Area "Cytokine therapy" applicable to this article?

Thanks for your feedback.
Stem cell therapy
Is the Subject Area "Stem cell therapy" applicable to this article?

Thanks for your feedback.
Lasers
Is the Subject Area "Lasers" applicable to this article?

Thanks for your feedback.
Toll-like receptors
Is the Subject Area "Toll-like receptors" applicable to this article?

Thanks for your feedback.