DNA Methyltransferase Inhibitor Zebularine Inhibits Human Hepatic Carcinoma Cells Proliferation and Induces Apoptosis

Open Access

Peer-reviewed

Research Article

Kazuaki Nakamura ,

* E-mail: nakamura-kz@ncchd.go.jp

Affiliation Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Kazuko Aizawa,

Affiliation Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Kazuhiko Nakabayashi,

Affiliation Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Natsuko Kato,

Affiliation Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Junji Yamauchi,

Affiliation Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Kenichiro Hata,

Affiliation Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan
⨯
Akito Tanoue

Affiliation Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
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Apoptosis
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DNA methylation
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Hepatocellular carcinoma
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Phosphorylation
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Cancer treatment
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Cell growth
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Japan
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MAPK signaling cascades
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