Structural Basis of the γ-Lactone-Ring Formation in Ascorbic Acid Biosynthesis by the Senescence Marker Protein-30/Gluconolactonase

• Shingo Aizawa,

  Affiliations Cellular Genetics, Graduate School of Science and Engineering, Tokyo Metropolitan University, Hachioji, Tokyo, Japan, Molecular Regulation of Aging, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan, Biomedicinal Information Research Center (BIRC), National Institute of Advanced Industrial Science and Technology (AIST), Koto-ku, Tokyo, Japan

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• Miki Senda,

  Affiliation Research and Development Department, Japan Biological Informatics Consortium (JBIC), Koto-ku, Tokyo, Japan

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• Ayaka Harada,

  Affiliations Biomedicinal Information Research Center (BIRC), National Institute of Advanced Industrial Science and Technology (AIST), Koto-ku, Tokyo, Japan, Materials Science and Engineering, Tokyo Denki University, Adachi-ku, Tokyo, Japan

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• Naoki Maruyama,

  Affiliation Molecular Regulation of Aging, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

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• Tetsuo Ishida,

  Affiliation Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Ohtsu, Shiga, Japan

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• Toshiro Aigaki,

  Affiliation Cellular Genetics, Graduate School of Science and Engineering, Tokyo Metropolitan University, Hachioji, Tokyo, Japan

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• Akihito Ishigami,

  Affiliation Molecular Regulation of Aging, Tokyo Metropolitan Institute of Gerontology, Itabashi-ku, Tokyo, Japan

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• Toshiya Senda

  * E-mail: toshiya-senda@aist.go.jp

  Affiliation Biomedicinal Information Research Center (BIRC), National Institute of Advanced Industrial Science and Technology (AIST), Koto-ku, Tokyo, Japan

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