Cerebrospinal Fluid PKR Level Predicts Cognitive Decline in Alzheimer’s Disease

Julien Dumurgier; Francois Mouton-Liger; Pauline Lapalus; Magali Prevot; Jean-Louis Laplanche; Jacques Hugon; Claire Paquet; for the Groupe d’Investigation du Liquide Cephalorachidien (GIL) Study Network

doi:10.1371/journal.pone.0053587

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Peer-reviewed

Research Article

Cerebrospinal Fluid PKR Level Predicts Cognitive Decline in Alzheimer’s Disease

Julien Dumurgier ,

Contributed equally to this work with: Julien Dumurgier, Francois Mouton-Liger, Jacques Hugon, Claire Paquet

Affiliations Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France, Institut du Fer à Moulin, Inserm UMR-S 839, Paris, France
⨯
Francois Mouton-Liger ,

Contributed equally to this work with: Julien Dumurgier, Francois Mouton-Liger, Jacques Hugon, Claire Paquet

Affiliation Institut du Fer à Moulin, Inserm UMR-S 839, Paris, France
⨯
Pauline Lapalus,

Affiliation Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France
⨯
Magali Prevot,

Affiliation Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France
⨯
Jean-Louis Laplanche,

Affiliation Department of Biochemistry Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France
⨯
Jacques Hugon ,

Contributed equally to this work with: Julien Dumurgier, Francois Mouton-Liger, Jacques Hugon, Claire Paquet

* E-mail: jacques.hugon@lrb.aphp.fr

Affiliations Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France, Institut du Fer à Moulin, Inserm UMR-S 839, Paris, France
⨯
Claire Paquet ,

Contributed equally to this work with: Julien Dumurgier, Francois Mouton-Liger, Jacques Hugon, Claire Paquet

Affiliations Clinical and Research Memory Center, Paris Nord Ile de France Saint Louis Lariboisière Fernand Hospital, AP-HP, University of Paris Diderot, Paris, France, Institut du Fer à Moulin, Inserm UMR-S 839, Paris, France
⨯
for the Groupe d’Investigation du Liquide Cephalorachidien (GIL) Study Network , for the Groupe d’Investigation du Liquide Cephalorachidien (GIL) Study Network

Cerebrospinal Fluid PKR Level Predicts Cognitive Decline in Alzheimer’s Disease

Julien Dumurgier,
Francois Mouton-Liger,
Pauline Lapalus,
Magali Prevot,
Jean-Louis Laplanche,
Jacques Hugon,
Claire Paquet,
for the Groupe d’Investigation du Liquide Cephalorachidien (GIL) Study Network

Published: January 8, 2013
https://doi.org/10.1371/journal.pone.0053587

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Cerebrospinal fluid
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Biomarkers
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Alzheimer's disease
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Lesions
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Memory
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