The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate

Tien Chye Tan; Oliver Spadiut; Thanyaporn Wongnate; Jeerus Sucharitakul; Iris Krondorfer; Christoph Sygmund; Dietmar Haltrich; Pimchai Chaiyen; Clemens K. Peterbauer; Christina Divne

doi:10.1371/journal.pone.0053567

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Research Article

The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate

Tien Chye Tan ,

Contributed equally to this work with: Tien Chye Tan, Oliver Spadiut

Affiliations School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯
Oliver Spadiut ,

Contributed equally to this work with: Tien Chye Tan, Oliver Spadiut

Affiliation School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden
⨯
Thanyaporn Wongnate,

Affiliation Department of Biochemistry and Center of Excellence in Protein Structure and Function, Faculty of Science, Mahidol University, Bangkok, Thailand
⨯
Jeerus Sucharitakul,

Affiliation Department of Biochemistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
⨯
Iris Krondorfer,

Affiliation Food Biotechnology Laboratory, BOKU University of Natural Resources and Life Sciences, Vienna, Austria
⨯
Christoph Sygmund,

Affiliation Food Biotechnology Laboratory, BOKU University of Natural Resources and Life Sciences, Vienna, Austria
⨯
Dietmar Haltrich,

Affiliation Food Biotechnology Laboratory, BOKU University of Natural Resources and Life Sciences, Vienna, Austria
⨯
Pimchai Chaiyen,

Affiliation Department of Biochemistry and Center of Excellence in Protein Structure and Function, Faculty of Science, Mahidol University, Bangkok, Thailand
⨯
Clemens K. Peterbauer,

Affiliation Food Biotechnology Laboratory, BOKU University of Natural Resources and Life Sciences, Vienna, Austria
⨯
Christina Divne

* E-mail: divne@biotech.kth.se

Affiliations School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
⨯

The 1.6 Å Crystal Structure of Pyranose Dehydrogenase from Agaricus meleagris Rationalizes Substrate Specificity and Reveals a Flavin Intermediate

Tien Chye Tan,
Oliver Spadiut,
Thanyaporn Wongnate,
Jeerus Sucharitakul,
Iris Krondorfer,
Christoph Sygmund,
Dietmar Haltrich,
Pimchai Chaiyen,
Clemens K. Peterbauer,
Christina Divne

Published: January 9, 2013
https://doi.org/10.1371/journal.pone.0053567

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