G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

Anne Müller; Gunnar Kleinau; Carolin L. Piechowski; Timo D. Müller; Brian Finan; Juliane Pratzka; Annette Grüters; Heiko Krude; Matthias Tschöp; Heike Biebermann

doi:10.1371/journal.pone.0053347

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Open Access

Peer-reviewed

Research Article

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

Anne Müller ,

Contributed equally to this work with: Anne Müller, Gunnar Kleinau

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Gunnar Kleinau ,

Contributed equally to this work with: Anne Müller, Gunnar Kleinau

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Carolin L. Piechowski,

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Timo D. Müller,

Affiliation Institute of Diabetes and Obesity, Helmholtz Center Munich, German Research Center for Environmental Health (GmbH), Munich, Germany
⨯
Brian Finan,

Affiliation Institute of Diabetes and Obesity, Helmholtz Center Munich, German Research Center for Environmental Health (GmbH), Munich, Germany
⨯
Juliane Pratzka,

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Annette Grüters,

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Heiko Krude,

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯
Matthias Tschöp,

Affiliations Institute of Diabetes and Obesity, Helmholtz Center Munich, German Research Center for Environmental Health (GmbH), Munich, Germany, Department of Metabolic Diseases, Technical University, Munich, Germany
⨯
Heike Biebermann

* E-mail: heike.biebermann@charite.de

Affiliation Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
⨯

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

Anne Müller,
Gunnar Kleinau,
Carolin L. Piechowski,
Timo D. Müller,
Brian Finan,
Juliane Pratzka,
Annette Grüters,
Heiko Krude,
Matthias Tschöp,
Heike Biebermann

Published: January 15, 2013
https://doi.org/10.1371/journal.pone.0053347

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Zinc
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Transfection
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G protein coupled receptors
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Signal processing
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G-protein signaling
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Reporter gene assay
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Crystal structure
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Hormone receptor signaling
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