Solid Phase Synthesis of Mitochondrial Triphenylphosphonium-Vitamin E Metabolite Using a Lysine Linker for Reversal of Oxidative Stress

Open Access

Peer-reviewed

Research Article

Mohanad Mossalam ,

* E-mail: mohanad.mossalam@utah.edu

Affiliation Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah, United States of America
⨯
Jamie Soto,

Affiliation Program in Molecular Medicine and Division of Endocrinology, Metabolism and Diabetes, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
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Carol S. Lim,

Affiliation Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah, United States of America
⨯
E. Dale Abel

Affiliation Program in Molecular Medicine and Division of Endocrinology, Metabolism and Diabetes, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
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Mitochondria
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Vitamin E
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Antioxidants
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Lysine
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Oxidative stress
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Solid phases
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Synthesis phase
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Reactive oxygen species
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