Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

Annalisa Bucchi; Mirko Baruscotti; Marco Nardini; Andrea Barbuti; Stefano Micheloni; Martino Bolognesi; Dario DiFrancesco

doi:10.1371/journal.pone.0053132

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Peer-reviewed

Research Article

Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

Annalisa Bucchi ,

Contributed equally to this work with: Annalisa Bucchi, Mirko Baruscotti

Affiliations The PaceLab, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy, Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata, Università degli Studi di Milano, Milano, Italy
⨯
Mirko Baruscotti ,

Contributed equally to this work with: Annalisa Bucchi, Mirko Baruscotti

Affiliations The PaceLab, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy, Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata, Università degli Studi di Milano, Milano, Italy
⨯
Marco Nardini,

Affiliation Laboratory of Protein Biochemistry, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Andrea Barbuti,

Affiliations The PaceLab, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy, Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata, Università degli Studi di Milano, Milano, Italy
⨯
Stefano Micheloni,

Affiliation The PaceLab, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Martino Bolognesi,

Affiliation Laboratory of Protein Biochemistry, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy
⨯
Dario DiFrancesco

* E-mail: dario.difrancesco@unimi.it

Affiliations The PaceLab, Department of Life Sciences, Università degli Studi di Milano, Milano, Italy, Centro Interuniversitario di Medicina Molecolare e Biofisica Applicata, Università degli Studi di Milano, Milano, Italy
⨯

Identification of the Molecular Site of Ivabradine Binding to HCN4 Channels

Annalisa Bucchi,
Mirko Baruscotti,
Marco Nardini,
Andrea Barbuti,
Stefano Micheloni,
Martino Bolognesi,
Dario DiFrancesco

Published: January 4, 2013
https://doi.org/10.1371/journal.pone.0053132

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