Alpha-Fetoprotein Promoter-Driven Cre/LoxP-Switched RNA Interference for Hepatocellular Carcinoma Tissue-Specific Target Therapy

Yuan-Fei Peng; Ying-Hong Shi; Zhen-Bin Ding; Jian Zhou; Shuang-Jian Qiu; Bo Hui; Cheng-Yu Gu; Hua Yang; Wei-Ren Liu; Jia Fan

doi:10.1371/journal.pone.0053072

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Open Access

Peer-reviewed

Research Article

Alpha-Fetoprotein Promoter-Driven Cre/LoxP-Switched RNA Interference for Hepatocellular Carcinoma Tissue-Specific Target Therapy

Yuan-Fei Peng ,

Contributed equally to this work with: Yuan-Fei Peng, Ying-Hong Shi

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Ying-Hong Shi ,

Contributed equally to this work with: Yuan-Fei Peng, Ying-Hong Shi

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Zhen-Bin Ding,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Jian Zhou,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Shuang-Jian Qiu,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Bo Hui,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Cheng-Yu Gu,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Hua Yang,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Wei-Ren Liu,

Affiliation Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China
⨯
Jia Fan

* E-mail: fan.jia@zs-hosptal.sh.cn

Affiliations Department of Liver Surgery, Liver Cancer Institute, Zhongshan Hospital, Fudan University; Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Shanghai, People's Republic of China, Institutes of Biomedical Sciences, Fudan University, Shanghai, People's Republic of China
⨯

Alpha-Fetoprotein Promoter-Driven Cre/LoxP-Switched RNA Interference for Hepatocellular Carcinoma Tissue-Specific Target Therapy

Yuan-Fei Peng,
Ying-Hong Shi,
Zhen-Bin Ding,
Jian Zhou,
Shuang-Jian Qiu,
Bo Hui,
Cheng-Yu Gu,
Hua Yang,
Wei-Ren Liu,
Jia Fan

Published: February 28, 2013
https://doi.org/10.1371/journal.pone.0053072

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