Differences in Transcription Patterns between Induced Pluripotent Stem Cells Produced from the Same Germ Layer Are Erased upon Differentiation

Iryna Pirozhkova; Ana Barat; Petr Dmitriev; Elena Kim; Thomas Robert; Justine Guégan; Chrystèle Bilhou-Nabera; Florence Busato; Jörg Tost; Gilles Carnac; Dalila Laoudj-Chenivesse; Marc Lipinski; Yegor Vassetzky

doi:10.1371/journal.pone.0053033

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Peer-reviewed

Research Article

Differences in Transcription Patterns between Induced Pluripotent Stem Cells Produced from the Same Germ Layer Are Erased upon Differentiation

Iryna Pirozhkova,

Current address: IPS/C Platform, Institut de cancérologie Gustave Roussy, Villejuif, France

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Ana Barat ,

Contributed equally to this work with: Ana Barat, Petr Dmitriev, Elena Kim

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Petr Dmitriev ,

Contributed equally to this work with: Ana Barat, Petr Dmitriev, Elena Kim

Affiliations CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France, INSERM U1046, Université Montpellier 1, Université Montpellier 2, Montpellier, France
⨯
Elena Kim ,

Contributed equally to this work with: Ana Barat, Petr Dmitriev, Elena Kim

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Thomas Robert,

Affiliation Integrated Biology Platform, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Justine Guégan,

Affiliation Integrated Biology Platform, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Chrystèle Bilhou-Nabera,

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Florence Busato,

Affiliation Laboratory of Epigenetics, Centre national de génotypage CEA-Institut de génomique, Evry, France
⨯
Jörg Tost,

Affiliations Laboratory of Epigenetics, Centre national de génotypage CEA-Institut de génomique, Evry, France, Laboratory for Functional Genomics, Fondation Jean Dausset – CEPH, Paris, France
⨯
Gilles Carnac,

Affiliation INSERM U1046, Université Montpellier 1, Université Montpellier 2, Montpellier, France
⨯
Dalila Laoudj-Chenivesse,

Affiliation INSERM U1046, Université Montpellier 1, Université Montpellier 2, Montpellier, France
⨯
Marc Lipinski,

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯
Yegor Vassetzky

* E-mail: vassetzky@igr.fr

Affiliation CNRS, Université Paris-Sud, UMR-8126, Institut de cancérologie Gustave Roussy, Villejuif, France
⨯

Differences in Transcription Patterns between Induced Pluripotent Stem Cells Produced from the Same Germ Layer Are Erased upon Differentiation

Iryna Pirozhkova,
Ana Barat,
Petr Dmitriev,
Elena Kim,
Thomas Robert,
Justine Guégan,
Chrystèle Bilhou-Nabera,
Florence Busato,
Jörg Tost,
Gilles Carnac

Published: January 9, 2013
https://doi.org/10.1371/journal.pone.0053033

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Myoblasts
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Induced pluripotent stem cells
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Fibroblasts
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Gene expression
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Cell differentiation
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