Human Sensory Neurons Derived from Induced Pluripotent Stem Cells Support Varicella-Zoster Virus Infection

Katherine S. Lee; Wenbo Zhou; Jonah J. Scott-McKean; Kaitlin L. Emmerling; Guang-yun Cai; David L. Krah; Alberto C. Costa; Curt R. Freed; Myron J. Levin

doi:10.1371/journal.pone.0053010

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Open Access

Peer-reviewed

Research Article

Human Sensory Neurons Derived from Induced Pluripotent Stem Cells Support Varicella-Zoster Virus Infection

Katherine S. Lee ,

* E-mail: Katherine.S.Lee@ucdenver.edu

Affiliation Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Wenbo Zhou ,

Contributed equally to this work with: Wenbo Zhou, Myron J. Levin

Affiliation Neuroscience Training Program, Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Jonah J. Scott-McKean,

Affiliation Neuroscience Training Program, Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Kaitlin L. Emmerling,

Affiliation Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Guang-yun Cai,

Affiliation Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
David L. Krah,

Affiliation Merck Sharp & Dohme Corporation, West Point, Pennsylvania, United States of America
⨯
Alberto C. Costa,

Affiliation Neuroscience Training Program, Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Curt R. Freed,

Affiliation Neuroscience Training Program, Division of Clinical Pharmacology and Toxicology, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America
⨯
Myron J. Levin

Contributed equally to this work with: Wenbo Zhou, Myron J. Levin

Affiliation Department of Pediatrics, Section of Infectious Diseases, University of Colorado Denver, Aurora, Colorado, United States of America
⨯

Human Sensory Neurons Derived from Induced Pluripotent Stem Cells Support Varicella-Zoster Virus Infection

Katherine S. Lee,
Wenbo Zhou,
Jonah J. Scott-McKean,
Kaitlin L. Emmerling,
Guang-yun Cai,
David L. Krah,
Alberto C. Costa,
Curt R. Freed,
Myron J. Levin

Published: December 28, 2012
https://doi.org/10.1371/journal.pone.0053010

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Induced pluripotent stem cells
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Neuronal differentiation
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