PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites

• Jürgen Glas ,

  Contributed equally to this work with: Jürgen Glas, Julia Seiderer

  Affiliations Department of Medicine II - Grosshadern, University of Munich, Munich, Germany, Department of Preventive Dentistry and Periodontology, University of Munich, Munich, Germany, Department of Human Genetics, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen, Aachen, Germany

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• Julia Seiderer ,

  Contributed equally to this work with: Jürgen Glas, Julia Seiderer

  Affiliation Department of Medicine II - Grosshadern, University of Munich, Munich, Germany

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• Darina Czamara,

  Affiliation Max-Planck-Institute of Psychiatry, Munich, Germany

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• Giulia Pasciuto,

  Affiliation Department of Medicine II - Grosshadern, University of Munich, Munich, Germany

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• Julia Diegelmann,

  Affiliations Department of Medicine II - Grosshadern, University of Munich, Munich, Germany, Department of Preventive Dentistry and Periodontology, University of Munich, Munich, Germany

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• Martin Wetzke,

  Affiliation Center for Pediatrics, Hannover Medical School, Hannover, Germany

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• Torsten Olszak,

  Affiliations Department of Medicine II - Grosshadern, University of Munich, Munich, Germany, Division of Gastroenterology, Brigham & Women's Hospital, Harvard Medical School, Boston, United States of America

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• Christiane Wolf,

  Affiliation Max-Planck-Institute of Psychiatry, Munich, Germany

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• Bertram Müller-Myhsok,

  Affiliation Max-Planck-Institute of Psychiatry, Munich, Germany

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• Tobias Balschun,

  Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany

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• Jean-Paul Achkar,

  Affiliations Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America, Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

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• M. Ilyas Kamboh,

  Affiliation Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Andre Franke,

  Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany

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• Richard H. Duerr,

  Affiliations Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Division of Gastroenterology, Hepatology and Nutrition, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

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• Stephan Brand

  * E-mail: Stephan.Brand@med.uni-muenchen.de

  Affiliation Department of Medicine II - Grosshadern, University of Munich, Munich, Germany

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