Yohimbine Enhances Protection of Berberine against LPS-Induced Mouse Lethality through Multiple Mechanisms

Hui Li; Yiyang Wang; Haoqing Zhang; Baoyin Jia; Daan Wang; Hongmei Li; Daxiang Lu; Renbin Qi; Yuxia Yan; Huadong Wang

doi:10.1371/journal.pone.0052863

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Open Access

Peer-reviewed

Research Article

Yohimbine Enhances Protection of Berberine against LPS-Induced Mouse Lethality through Multiple Mechanisms

Hui Li ,

Contributed equally to this work with: Hui Li, Yiyang Wang

Affiliation Department of Otolaryngology, Guangzhou Overseas Chinese Hospital, School of Medicine, Jinan University, Guangzhou, China
⨯
Yiyang Wang ,

Contributed equally to this work with: Hui Li, Yiyang Wang

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Haoqing Zhang,

Affiliation Center of Prenatal Diagnosis, Chenzhou No. 1 People’s Hospital, Chenzhou, Hunan, China
⨯
Baoyin Jia,

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Daan Wang,

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Hongmei Li,

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Daxiang Lu,

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Renbin Qi,

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯
Yuxia Yan,

Affiliation Department of Biochemistry, School of Medicine, Jinan University, Guangzhou, China
⨯
Huadong Wang

* E-mail: owanghd@jnu.edu.cn

Affiliation Department of Pathophysiology, Key Laboratory of State Administration of Traditional Chinese Medicine of the People’s Republic of China, School of Medicine, Jinan University, Guangzhou, China
⨯

Yohimbine Enhances Protection of Berberine against LPS-Induced Mouse Lethality through Multiple Mechanisms

Hui Li,
Yiyang Wang,
Haoqing Zhang,
Baoyin Jia,
Daan Wang,
Hongmei Li,
Daxiang Lu,
Renbin Qi,
Yuxia Yan,
Huadong Wang

Published: December 28, 2012
https://doi.org/10.1371/journal.pone.0052863

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