Mathematical Model of Metabolism and Electrophysiology of Amino Acid and Glucose Stimulated Insulin Secretion: In Vitro Validation Using a β-Cell Line

Open Access

Peer-reviewed

Research Article

Manuela Salvucci ,

* E-mail: manuela.salvucci@gmail.com

Affiliation School of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland
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Zoltan Neufeld,

Affiliation School of Mathematics and Physics, University of Queensland, Brisbane, Australia
⨯
Philip Newsholme

Affiliations School of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland, School of Biomedical Sciences, Curtin University, Perth, Australia
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Glucose
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Insulin secretion
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Membrane metabolism
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Cell membranes
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Insulin
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Membrane potential
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Mathematical models
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Mitochondria
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