Morphological Characteristics of Motor Neurons Do Not Determine Their Relative Susceptibility to Degeneration in a Mouse Model of Severe Spinal Muscular Atrophy

Sophie R. Thomson; Joya E. Nahon; Chantal A. Mutsaers; Derek Thomson; Gillian Hamilton; Simon H. Parson; Thomas H. Gillingwater

doi:10.1371/journal.pone.0052605

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Research Article

Morphological Characteristics of Motor Neurons Do Not Determine Their Relative Susceptibility to Degeneration in a Mouse Model of Severe Spinal Muscular Atrophy

Sophie R. Thomson ,

Contributed equally to this work with: Sophie R. Thomson, Joya E. Nahon

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Joya E. Nahon ,

Contributed equally to this work with: Sophie R. Thomson, Joya E. Nahon

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Chantal A. Mutsaers,

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Derek Thomson,

Affiliation Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom
⨯
Gillian Hamilton,

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Simon H. Parson,

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Thomas H. Gillingwater

* E-mail: T.Gillingwater@ed.ac.uk

Affiliations Euan MacDonald Centre for Motor Neurone Disease Research, University of Edinburgh, Edinburgh, United Kingdom, Centre for Integrative Physiology, University of Edinburgh, Edinburgh, United Kingdom
⨯

Morphological Characteristics of Motor Neurons Do Not Determine Their Relative Susceptibility to Degeneration in a Mouse Model of Severe Spinal Muscular Atrophy

Sophie R. Thomson,
Joya E. Nahon,
Chantal A. Mutsaers,
Derek Thomson,
Gillian Hamilton,
Simon H. Parson,
Thomas H. Gillingwater

Published: December 20, 2012
https://doi.org/10.1371/journal.pone.0052605

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