Overexpressing 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGR) in the Lactococcal Mevalonate Pathway for Heterologous Plant Sesquiterpene Production

Adelene Ai-Lian Song; Janna Ong Abdullah; Mohd. Puad Abdullah; Norazizah Shafee; Roohaida Othman; Ee-Fun Tan; Normah Mohd. Noor; Abdul Rahim Raha

doi:10.1371/journal.pone.0052444

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Peer-reviewed

Research Article

Overexpressing 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGR) in the Lactococcal Mevalonate Pathway for Heterologous Plant Sesquiterpene Production

Adelene Ai-Lian Song,

Affiliation Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
⨯
Janna Ong Abdullah,

Affiliation Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
⨯
Mohd. Puad Abdullah,

Affiliation Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
⨯
Norazizah Shafee,

Affiliation Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
⨯
Roohaida Othman,

Affiliation Institute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor Darul Ehsan, Malaysia
⨯
Ee-Fun Tan,

Affiliation School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Selangor Darul Ehsan, Malaysia
⨯
Normah Mohd. Noor,

Affiliation Institute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor Darul Ehsan, Malaysia
⨯
Abdul Rahim Raha

* E-mail: raha@biotech.upm.edu.my

Affiliations Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia
⨯

Overexpressing 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGR) in the Lactococcal Mevalonate Pathway for Heterologous Plant Sesquiterpene Production

Adelene Ai-Lian Song,
Janna Ong Abdullah,
Mohd. Puad Abdullah,
Norazizah Shafee,
Roohaida Othman,
Ee-Fun Tan,
Normah Mohd. Noor,
Abdul Rahim Raha

Published: December 26, 2012
https://doi.org/10.1371/journal.pone.0052444

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Lactococcus lactis
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Isoprenoids
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Cloning
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