C. elegans Expressing Human β2-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

Luisa Diomede; Cristina Soria; Margherita Romeo; Sofia Giorgetti; Loredana Marchese; Patrizia Palma Mangione; Riccardo Porcari; Irene Zorzoli; Mario Salmona; Vittorio Bellotti; Monica Stoppini

doi:10.1371/journal.pone.0052314

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Peer-reviewed

Research Article

C. elegans Expressing Human β₂-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

Luisa Diomede,

Affiliation Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Cristina Soria,

Affiliation Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy
⨯
Margherita Romeo,

Affiliation Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Sofia Giorgetti,

Affiliation Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy
⨯
Loredana Marchese,

Affiliation Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy
⨯
Patrizia Palma Mangione,

Affiliations Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, United Kingdom
⨯
Riccardo Porcari,

Affiliation Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy
⨯
Irene Zorzoli,

Affiliation Department of Internal Medicine and Clinical Therapeutics, University of Pavia, Pavia, Italy
⨯
Mario Salmona,

Affiliation Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
⨯
Vittorio Bellotti ,

* E-mail: vbellot@unipv.it

Affiliations Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, Royal Free Campus, University College London, London, United Kingdom
⨯
Monica Stoppini

Affiliation Department of Molecular Medicine, Institute of Biochemistry, University of Pavia, Pavia, Italy
⨯

C. elegans Expressing Human β₂-Microglobulin: A Novel Model for Studying the Relationship between the Molecular Assembly and the Toxic Phenotype

Luisa Diomede,
Cristina Soria,
Margherita Romeo,
Sofia Giorgetti,
Loredana Marchese,
Patrizia Palma Mangione,
Riccardo Porcari,
Irene Zorzoli,
Mario Salmona,
Vittorio Bellotti

Published: December 21, 2012
https://doi.org/10.1371/journal.pone.0052314

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