Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells

Yuchen Liu; Yonghua Han; Hu Zhang; Liping Nie; Zhimao Jiang; Pingping Fa; Yaoting Gui; Zhiming Cai

doi:10.1371/journal.pone.0052280

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Peer-reviewed

Research Article

Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells

Yuchen Liu ,

Contributed equally to this work with: Yuchen Liu, Yonghua Han

Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China, Anhui Medical University, Hefei, People's Republic of China, Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, People's Republic of China
⨯
Yonghua Han ,

Contributed equally to this work with: Yuchen Liu, Yonghua Han

Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China, Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, People's Republic of China
⨯
Hu Zhang,

Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China, Anhui Medical University, Hefei, People's Republic of China
⨯
Liping Nie,

Affiliation Department of Clinical Laboratory, Peking University Shenzhen Hospital, Shenzhen, People's Republic of China
⨯
Zhimao Jiang,

Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China
⨯
Pingping Fa,

Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China
⨯
Yaoting Gui ,

* E-mail: caizhiming2000@yahoo.com.cn (ZC); guiyaoting2007@yahoo.com.cn (YG)

Affiliation Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China
⨯
Zhiming Cai

* E-mail: caizhiming2000@yahoo.com.cn (ZC); guiyaoting2007@yahoo.com.cn (YG)

Affiliations Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen, People's Republic of China, Shenzhen Key Laboratory of Genitourinary Tumor, Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, Shenzhen, People's Republic of China
⨯

Synthetic miRNA-Mowers Targeting miR-183-96-182 Cluster or miR-210 Inhibit Growth and Migration and Induce Apoptosis in Bladder Cancer Cells

Yuchen Liu,
Yonghua Han,
Hu Zhang,
Liping Nie,
Zhimao Jiang,
Pingping Fa,
Yaoting Gui,
Zhiming Cai

Published: December 17, 2012
https://doi.org/10.1371/journal.pone.0052280

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MicroRNAs
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Bladder cancer
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Transfection
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