Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer Patients

Pablo Martinez; Javier Hernández-Losa; Ma Ángeles Montero; Susana Cedrés; Josep Castellví; Alex Martinez-Marti; Natalia Tallada; Nuria Murtra-Garrell; Alejandro Navarro-Mendivill; Victor Rodriguez-Freixinos; Mercedes Canela; Santiago Ramon y Cajal; Enriqueta Felip

doi:10.1371/journal.pone.0052261

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Open Access

Peer-reviewed

Research Article

Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer Patients

Pablo Martinez ,

* E-mail: pamartinez@vhebron.net

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Javier Hernández-Losa,

Affiliation Pathology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Ma Ángeles Montero,

Affiliation Pathology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Susana Cedrés,

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Josep Castellví,

Affiliation Pathology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Alex Martinez-Marti,

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Natalia Tallada,

Affiliation Pathology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Nuria Murtra-Garrell,

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Alejandro Navarro-Mendivill,

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Victor Rodriguez-Freixinos,

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Mercedes Canela,

Affiliation Thoracic Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Santiago Ramon y Cajal,

Affiliation Pathology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯
Enriqueta Felip

Affiliation Medical Oncology Department, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona, Barcelona, Spain
⨯

Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer Patients

Pablo Martinez,
Javier Hernández-Losa,
Ma Ángeles Montero,
Susana Cedrés,
Josep Castellví,
Alex Martinez-Marti,
Natalia Tallada,
Nuria Murtra-Garrell,
Alejandro Navarro-Mendivill,
Victor Rodriguez-Freixinos

Published: January 24, 2013
https://doi.org/10.1371/journal.pone.0052261

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Non-small cell lung cancer
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Cancer treatment
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Immunohistochemistry techniques
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Adenocarcinoma
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Fluorescent in situ hybridization
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Polymerase chain reaction
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Histology
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Diagnostic medicine
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