Investigation of Testosterone, Androstenone, and Estradiol Metabolism in HepG2 Cells and Primary Culture Pig Hepatocytes and Their Effects on 17βHSD7 Gene Expression

Gang Chen; Sicong Li; Xinxing Dong; Ying Bai; Ailiang Chen; Shuming Yang; Meiying Fang; Galia Zamaratskaia; Olena Doran

doi:10.1371/journal.pone.0052255

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Open Access

Peer-reviewed

Research Article

Investigation of Testosterone, Androstenone, and Estradiol Metabolism in HepG2 Cells and Primary Culture Pig Hepatocytes and Their Effects on 17βHSD7 Gene Expression

Gang Chen,

Affiliation Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China
⨯
Sicong Li,

Affiliation Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China
⨯
Xinxing Dong,

Affiliation College of Animal Science and Technology, China Agricultural University, Beijing, China
⨯
Ying Bai,

Affiliation College of Animal Science and Technology, China Agricultural University, Beijing, China
⨯
Ailiang Chen,

Affiliation Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China
⨯
Shuming Yang,

Affiliation Key Laboratory of Agro-Product Quality and Safety, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China
⨯
Meiying Fang ,

* E-mail: meiying@cau.edu.cn

Affiliation College of Animal Science and Technology, China Agricultural University, Beijing, China
⨯
Galia Zamaratskaia,

Affiliation Department of Food Science, Swedish University of Agriculture Science (SLU), Uppsala, Sweden
⨯
Olena Doran

Affiliation Centre for Research in Biosciences, Faculty of Health and Life Sciences, University of the West of England, Bristol, United Kingdom
⨯

Investigation of Testosterone, Androstenone, and Estradiol Metabolism in HepG2 Cells and Primary Culture Pig Hepatocytes and Their Effects on 17βHSD7 Gene Expression

Gang Chen,
Sicong Li,
Xinxing Dong,
Ying Bai,
Ailiang Chen,
Shuming Yang,
Meiying Fang,
Galia Zamaratskaia,
Olena Doran

Published: December 26, 2012
https://doi.org/10.1371/journal.pone.0052255

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