Engagement of SIRPα Inhibits Growth and Induces Programmed Cell Death in Acute Myeloid Leukemia Cells

• Mahban Irandoust ,

  Contributed equally to this work with: Mahban Irandoust, Julian Alvarez Zarate

  Affiliations Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands, Department of Hematology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Julian Alvarez Zarate ,

  Contributed equally to this work with: Mahban Irandoust, Julian Alvarez Zarate

  Affiliation Sanquin Research & Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Isabelle Hubeek,

  Affiliations Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands, Department of Hematology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Ellen M. van Beek,

  Affiliation Sanquin Research & Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Karin Schornagel,

  Affiliation Sanquin Research & Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Aart J. F. Broekhuizen,

  Affiliation Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Mercan Akyuz,

  Affiliation Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Arjan A. van de Loosdrecht,

  Affiliation Department of Hematology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Ruud Delwel,

  Affiliation Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Peter J. Valk,

  Affiliation Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Edwin Sonneveld,

  Affiliation Dutch Childhood Oncology Group (DCOG), The Hague, The Netherlands

  ⨯
• Pamela Kearns,

  Affiliation School of Cancer Sciences, University of Birmingham, Birmingham, United Kingdom

  ⨯
• Ursula Creutzig,

  Affiliation Department of Pediatric Hematology/Oncology, Medical School Hannover, Hannover, Germany

  ⨯
• Dirk Reinhardt,

  Affiliation Department of Pediatric Hematology/Oncology, Medical School Hannover, Hannover, Germany

  ⨯
• Eveline S. J. M. de Bont,

  Affiliation University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Eva A. Coenen,

  Affiliation Department of Pediatric Hematology/Oncology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands

  ⨯
• Marry M. van den Heuvel-Eibrink,

  Affiliation Department of Pediatric Hematology/Oncology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands

  ⨯
• C. Michel Zwaan,

  Affiliation Department of Pediatric Hematology/Oncology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands

  ⨯
• Gertjan J. L. Kaspers,

  Affiliation Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands

  ⨯
• Jacqueline Cloos ,

  ¶These authors also contributed equally to this work.

  Affiliations Department of Pediatric Hematology/Oncology, VU University Medical Centre, Amsterdam, The Netherlands, Department of Hematology, VU University Medical Centre, Amsterdam, The Netherlands

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•  [ ... ],
• Timo K. van den Berg

  * E-mail: t.k.vandenberg@sanquin.nl

  ¶These authors also contributed equally to this work.

  Affiliation Sanquin Research & Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

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