Methylphenidate Enhances NMDA-Receptor Response in Medial Prefrontal Cortex via Sigma-1 Receptor: A Novel Mechanism for Methylphenidate Action

• Chun-Lei Zhang ,

  Contributed equally to this work with: Chun-Lei Zhang, Ze-Jun Feng

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Ze-Jun Feng ,

  Contributed equally to this work with: Chun-Lei Zhang, Ze-Jun Feng

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Yue Liu,

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Xiao-Hua Ji,

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Ji-Yun Peng,

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Xue-Han Zhang,

  Affiliation Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China

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• Xue-Chu Zhen,

  Affiliation Neuropharmacological Laboratory, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

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• Bao-Ming Li

  * E-mail: bmli@fudan.edu.cn

  Affiliations Institute of Neurobiology and State Key laboratory of Medical Neurobiology, Institutes of Brain Science, Fudan University, Shanghai, China, Center for Neuropsychiatric Disorders, Institute of Life Science, Nanchang University, Nanchang, China

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