The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli

Gaetano Invernizzi; Francesco A. Aprile; Antonino Natalello; Andrea Ghisleni; Amanda Penco; Annalisa Relini; Silvia M. Doglia; Paolo Tortora; Maria E. Regonesi

doi:10.1371/journal.pone.0051890

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Peer-reviewed

Research Article

The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli

Gaetano Invernizzi ,

Contributed equally to this work with: Gaetano Invernizzi, Francesco A. Aprile

* E-mail: gaetano.invernizzi@unimib.it (GI); paolo.tortora@unimib.it (PT)

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Francesco A. Aprile ,

Contributed equally to this work with: Gaetano Invernizzi, Francesco A. Aprile

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Antonino Natalello,

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Andrea Ghisleni,

Current address: King’s College London, Muscle Signaling and Development, The Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, London, United Kingdom

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Amanda Penco,

Affiliation Department of Physics, University of Genoa, Genoa, Italy
⨯
Annalisa Relini,

Affiliation Department of Physics, University of Genoa, Genoa, Italy
⨯
Silvia M. Doglia,

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Paolo Tortora ,

* E-mail: gaetano.invernizzi@unimib.it (GI); paolo.tortora@unimib.it (PT)

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯
Maria E. Regonesi

Affiliation Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Milan, Italy
⨯

The Relationship between Aggregation and Toxicity of Polyglutamine-Containing Ataxin-3 in the Intracellular Environment of Escherichia coli

Gaetano Invernizzi,
Francesco A. Aprile,
Antonino Natalello,
Andrea Ghisleni,
Amanda Penco,
Annalisa Relini,
Silvia M. Doglia,
Paolo Tortora,
Maria E. Regonesi

Published: December 14, 2012
https://doi.org/10.1371/journal.pone.0051890

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