Interleukin-15-Induced CD56+ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

Sébastien Anguille; Eva Lion; Jurjen Tel; I. Jolanda M de Vries; Karen Couderé; Phillip D. Fromm; Viggo F. Van Tendeloo; Evelien L. Smits; Zwi N. Berneman

doi:10.1371/journal.pone.0051851

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Open Access

Peer-reviewed

Research Article

Interleukin-15-Induced CD56⁺ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

Sébastien Anguille ,

* E-mail: sebastien.anguille@uza.be

Affiliations University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium, Antwerp University Hospital, Center for Cell Therapy and Regenerative Medicine, Antwerp, Belgium
⨯
Eva Lion,

Affiliation University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium
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Jurjen Tel,

Affiliation Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Department of Tumor Immunology, Nijmegen, The Netherlands
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I. Jolanda M de Vries,

Affiliation Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Department of Tumor Immunology, Nijmegen, The Netherlands
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Karen Couderé,

Affiliation University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium
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Phillip D. Fromm,

Affiliation ANZAC Research Institute, Dendritic Cell Biology and Therapeutics Group, Sydney, Australia
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Viggo F. Van Tendeloo,

Affiliation University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium
⨯
Evelien L. Smits ,

Contributed equally to this work with: Evelien L. Smits, Zwi N. Berneman

Affiliations University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium, Antwerp University Hospital, Center for Cell Therapy and Regenerative Medicine, Antwerp, Belgium
⨯
Zwi N. Berneman

Contributed equally to this work with: Evelien L. Smits, Zwi N. Berneman

Affiliations University of Antwerp, Faculty of Medicine and Health Sciences, Vaccine and Infectious Disease Institute (VAXINFECTIO), Laboratory of Experimental Hematology, Antwerp, Belgium, Antwerp University Hospital, Center for Cell Therapy and Regenerative Medicine, Antwerp, Belgium
⨯

Interleukin-15-Induced CD56⁺ Myeloid Dendritic Cells Combine Potent Tumor Antigen Presentation with Direct Tumoricidal Potential

Sébastien Anguille,
Eva Lion,
Jurjen Tel,
I. Jolanda M de Vries,
Karen Couderé,
Phillip D. Fromm,
Viggo F. Van Tendeloo,
Evelien L. Smits,
Zwi N. Berneman

Published: December 28, 2012
https://doi.org/10.1371/journal.pone.0051851

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