Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer

Rachida Nachat-Kappes; Alexandre Pinel; Kristell Combe; Bruno Lamas; Marie-Chantal Farges; Adrien Rossary; Nicolas Goncalves-Mendes; Florence Caldefie-Chezet; Marie-Paule Vasson; Samar Basu

doi:10.1371/journal.pone.0051525

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Peer-reviewed

Research Article

Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer

Rachida Nachat-Kappes,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Alexandre Pinel,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Kristell Combe,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Bruno Lamas,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Marie-Chantal Farges,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Adrien Rossary,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Nicolas Goncalves-Mendes,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Florence Caldefie-Chezet,

Affiliation Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France
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Marie-Paule Vasson,

Affiliations Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France, Centre de Lutte Contre le Cancer Jean Perrin, Unité de Nutrition, Clermont-Ferrand, France, CHU Clermont-Ferrand, Service Nutrition, Clermont-Ferrand, France
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Samar Basu

* E-mail: samar.basu@udamail.fr

Affiliations Chaire d’Excellence Program, Biochemistry, Molecular Biology and Nutrition, Université d'Auvergne, Unité de Nutrition Humaine, Equipe ECRIN, CLARA, CRNH Auvergne; INRA, UMR, UNH, CRNH Auvergne, Clermont-Ferrand, France, Oxidative Stress and Inflammation, Department of Public Health and Caring Sciences, Faculty of Medicine, Uppsala University, Uppsala, Sweden
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Effects of Enriched Environment on COX-2, Leptin and Eicosanoids in a Mouse Model of Breast Cancer

Rachida Nachat-Kappes,
Alexandre Pinel,
Kristell Combe,
Bruno Lamas,
Marie-Chantal Farges,
Adrien Rossary,
Nicolas Goncalves-Mendes,
Florence Caldefie-Chezet,
Marie-Paule Vasson,
Samar Basu

Published: December 13, 2012
https://doi.org/10.1371/journal.pone.0051525

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Mouse models
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Immunofluorescence staining
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Breast tumors
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