Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

Shuijun Zhang; Gongquan Li; Yongfu Zhao; Guangzhi Liu; Yu Wang; Xiuxian Ma; Dexu Li; Yang Wu; Jianfeng Lu

doi:10.1371/journal.pone.0051461

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Peer-reviewed

Research Article

Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

Shuijun Zhang ,

* E-mail: zhangshuijun@zzu.edu.cn (SZ); jialu@umich.edu (JL)

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Gongquan Li,

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Yongfu Zhao,

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Guangzhi Liu,

Affiliation Department of Obstetrics and Gynecology, Henan Provincial Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China
⨯
Yu Wang,

Affiliation Department of Obstetrics and Gynecology, Henan Provincial Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China
⨯
Xiuxian Ma,

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Dexu Li,

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Yang Wu,

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, Key Laboratory of Hepatobiliary and Pancreatic Surgery & Digestive Organ Transplantation of Henan Province, Henan, People’s Republic of China
⨯
Jianfeng Lu

* E-mail: zhangshuijun@zzu.edu.cn (SZ); jialu@umich.edu (JL)

Affiliations Department of Hepatobiliary and Pancreatic Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan, United States of America
⨯

Smac Mimetic SM-164 Potentiates APO2L/TRAIL- and Doxorubicin-Mediated Anticancer Activity in Human Hepatocellular Carcinoma Cells

Shuijun Zhang,
Gongquan Li,
Yongfu Zhao,
Guangzhi Liu,
Yu Wang,
Xiuxian Ma,
Dexu Li,
Yang Wu,
Jianfeng Lu

Published: December 11, 2012
https://doi.org/10.1371/journal.pone.0051461

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