Retinal Arterioles Narrow with Increasing Duration of Anti-Retroviral Therapy in HIV Infection: A Novel Estimator of Vascular Risk in HIV?

Sophia Pathai; Helen A. Weiss; Stephen D. Lawn; Tunde Peto; Leris M. D’Costa; Colin Cook; Tien Y. Wong; Clare E. Gilbert

doi:10.1371/journal.pone.0051405

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Open Access

Peer-reviewed

Research Article

Retinal Arterioles Narrow with Increasing Duration of Anti-Retroviral Therapy in HIV Infection: A Novel Estimator of Vascular Risk in HIV?

Sophia Pathai ,

* E-mail: sophia.pathai@lshtm.ac.uk (SP); clare.gilbert@lshtm.ac.uk (CEG)

Affiliations International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom, Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
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Helen A. Weiss,

Affiliation MRC Tropical Epidemiology Group, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Stephen D. Lawn,

Affiliations Desmond Tutu HIV Centre, Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Tunde Peto,

Affiliation NIHR Biomedical Research Centre for Ophthalmology, at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
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Leris M. D’Costa,

Affiliation International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
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Colin Cook,

Affiliation Department of Ophthalmology, Faculty of Health Sciences, University of Cape Town, Groote Schuur Hospital, Cape Town, South Africa
⨯
Tien Y. Wong,

Affiliation Singapore Eye Research Institute, National University of Singapore, Singapore, Singapore
⨯
Clare E. Gilbert

* E-mail: sophia.pathai@lshtm.ac.uk (SP); clare.gilbert@lshtm.ac.uk (CEG)

Affiliation International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
⨯

Retinal Arterioles Narrow with Increasing Duration of Anti-Retroviral Therapy in HIV Infection: A Novel Estimator of Vascular Risk in HIV?

Sophia Pathai,
Helen A. Weiss,
Stephen D. Lawn,
Tunde Peto,
Leris M. D’Costa,
Colin Cook,
Tien Y. Wong,
Clare E. Gilbert

Published: December 10, 2012
https://doi.org/10.1371/journal.pone.0051405

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Highly-active antiretroviral therapy
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Retinal vessels
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HIV
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Cardiovascular disease risk
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Viral load
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Hypertension
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Arterioles
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HIV infections
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