Enrichment of Mutations in Multiple DNA Sequences Using COLD-PCR in Emulsion

Open Access

Peer-reviewed

Research Article

Elena Castellanos-Rizaldos,

Affiliation Division of DNA Repair and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
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Coren Audrey Milbury,

Affiliation Division of DNA Repair and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America
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G. Mike Makrigiorgos

* E-mail: mmakrigiorgos@lroc.harvard.edu

Affiliations Division of DNA Repair and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America, Division of Medical Physics and Biophysics, Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
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Emulsions
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Polymerase chain reaction
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Mutation
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Signal amplification
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Oils
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DNA denaturation
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Human genomics
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Mutation detection
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